Sos Sargsyan (24 October 1929 – 26 September 2013) was a prominent Armenian actor, director and writer.

Sos Sargsyan was born in Stepanavan in northern Armenia, at the time part of the Soviet Union. He moved to Yerevan in 1948 and started to perform at the Theater of the Young Spectator. He graduated from the Fine Arts and Theater Institute in 1954 as an actor. Between 1954 and 1991 he performed at the Sundukyan State Academic Theatre of Yerevan.

In October 1991, a month after Armenia's independence from the Soviet Union, Sargsyan took part in the first presidential election in independent Armenia. He was nominated by the Armenian Revolutionary Federation. In 1991 he established the Hamazgayin (Pan-National) Theater, which he headed until his death.From 1997 to 2006 he was the rector of the Yerevan Cinema and Theatre Institute. Sargsyan died on 26 September 2013 in Yerevan. Sargsyan's funeral was held on 29 September in attendance of Armenia's President Serzh Sargsyan and thousands of people. He was buried at the Komitas Pantheon.

Sargsyan started acting in 1947. Some of his most notable roles include Don Quixote, Iago, King John, King Lear, etc. He starred in over 40 films, mostly Armenian. Besides Armenian films he has starred in a number of Russian films, most notable of which is Solaris (1972), directed by Andrei Tarkovsky.